NU-CCNE Oligonucleotide Synthesis and Nanoconstructs Core
Primary Objectives
- To optimize and scale the spherical nucleic acid (SNA) platform for all projects in the CCNE
Approach
- Optimize constructions for intended applications (e.g., nanoparticle core composition, oligonucleotide sequence and loading, incorporation of ancillary ligands)
- Provide a standardized, scalable platform to screen in vitro efficacy of SNAs