Adam Silverman
Chemical & Biological Engineering
Faculty Mentors: Michael Jewett and Julius Lucks
Research
Adam Silverman received a B.S .in Chemical Engineering from Georgia Tech. His research is currently focused on developing inexpensive and user-friendly diagnostics for detecting pollutants in drinking water by harnessing natural biological sensors from bacteria and using them to produce outputs that are visible to the naked eye.
Awards & Fellowships
- National Institutes of Health Biotechnology Training Program Trainee (2017-2018)
- Cabell Fellowship (2016)
- George C. Thodos Teaching Assistant Award (2018)
Publications
- Silverman, A. D.; Kelley-Loughnane, N.; Lucks, J. B.; Jewett, M. C., “Deconstructing Cell-Free Extract Preparation for in Vitro Activation of Transcriptional Genetic Circuitry,” ACS Synthetic Biology,2019, 8 (2), 403-414.
- McNerney, M. P.; Zhang, Y.; Steppe, P.; Silverman, A. D.; Jewett, M. C.; Styczynski, M. P., “Point-of-care Biomarker Quantification Enabled by Sample-specific Calibration,” Science Advances,2019, 5 (9), eaax4473.
- Silverman, A.D.; A.S. Karim; and M.C. Jewett, “Cell-free Gene Expression: An Expanded Repertoire of Applications,” Nature Reviews Genetics, 2019. In press.
- Meyer, A.; Saaem, I.; Silverman, A.; Varaljay, V. A.; Mickol, R.; Blum, S.; Tobias, A. V.; Schwalm, N. D.; Mojadedi, W.; Onderko, E.; Bristol, C.; Liu, S.; Pratt, K.; Casini, A.; Eluere, R.; Moser, F.; Drake, C.; Gupta, M.; Kelley-Loughnane, N.; Lucks, J. P.; Akingbade, K. L.; Lux, M. P.; Glaven, S.; Crookes-Goodson, W.; Jewett, M. C.; Gordon, D. B.; Voigt, C. A., “Organism Engineering for the Bioproduction of the Triaminotrinitrobenzene (TATB) Precursor Phloroglucinol (PG),” ACS Synthetic Biology,2019, 8 (12), 2746-2755.
- Thavarajah, W.; Silverman, A. D.; Verosloff, M.; Kelley-Loughnane, N.; Jewett, M. C.; Lucks, J. B., “Point-of-Use Detection of Environmental Fluoride via a Cell-Free Riboswitch-Based Biosensor, ACS Synthetic Biology,2019. In press.
- Liu, X.; Silverman, A. D.; Alam, K. K.; Iverson, E.; Lucks, J. B.; Jewett, M. C.; Raman, S. Design of a Transcriptional Biosensor for the Portable, On-demand Detection of Cyanuric Acid, ACS Synthetic Biology,2019. In press.
- Silverman, A.D.; Akova, U.; Alam, K.K.; Jewett, M.C.; Lucks, J.B., “Design and Optimization of a Cell-free Atrazine Biosensor, bioRxiv, 2019.
Inventions
- “On-Demand, Portable Molecular Sensing Platform,” Jewett, M.C.; Lucks, J.B.; Silverman, A.D.; Alam, K.K., Serial No. 62/714,427, August 3, 2018.
- “Riboswitch-based Fluoride Sensing in Cell-free Extract,” Lucks, J.B.; Jewett, M.C.; Silverman, A.D.; Thavarajah, W., Serial No. 62/813,368, March 4, 2019.
- “Ultrasensitive and Multiplexed Cell-free Biosensors Using Cascaded Amplification and Positive Feedback,” Lucks, J.B.; Jewett, M.C.; Silverman, A.D., Provisional filed December 4, 2019.